Somali Government officials confirmed that at least 30 people were killed and more than 90 were wounded following a truck bomb attack south of the city on Saturday.
The blast coordinated by a suicide lorry bomber exploded at a busy ex control junction during rush hour.
According to the Mayor of Mogadishu, Omar Mohamed Mohamud who visited the scene the number of casualties might go up.
Among the dead include university students whose bus were caught up in the attack, security agencies manning the checkpoint, small business owners and pedestrians.
The blast comes amid heightened security across the city in past months to avert such attacks.
No group has so far claimed the responsibility for the attack but the Mayor of Mogadishu has blamed it on the armed group al-Shabaab.
The group has frequently carried out attacks in Somali capital targeting the Federal Government of Somalia installations and business centers.